MUST-READ EDITORIAL

The 2025 KDIGO IgA nephropathy guideline update: an ERA Immunonephrology Working Group perspective 

PRO / CON DEBATE
Age-adapted versus age-independent eGFR thresholds to diagnose CKD: integrating the debate and charting a balanced path forward 

TEN TIPS
Ten tips to teach learners to love nephrology (and recruit the next generation) 

SELECTED ORIGINAL ARTICLES

Clinical outcomes in Fabry patients switching to agalsidase beta for renal ineffectiveness of the primary Fabry therapy: a single-centre analysis 

Reducing intradialytic hypotension with intermittent pneumatic compression during haemodialysis: a randomized controlled trial 

Dosing, treatment patterns and safety of finerenone 
use in routine care: an interim analysis of the prospective, real-world and observational FINE-REAL study 
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Hypoglycaemia episodes  in older diabetic adults  undergoing haemodialysis  
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Tolvaptan in Autosomal Dominant Polycystic Kidney Disease (ADPKD): a multicenter real life Italian experience 
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Continuous measurement of pulse arrival time for identification of blood pressure changes in patients undergoing hemodialysis—a feasibility study  
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CELEBRATING THE TEAM BEHIND THE JOURNAL
Every issue of CKJ represents the culmination of countless hours of dedication, collaboration, and expertise, not only from our authors, editors, and reviewers, but also from the many individuals who work diligently behind the scenes. In our next Newsletters, we want to recognize and thank the people who make our publication possible and ask them to select their all-time favorite CKJ article.
MEET HEATHER WALKER (UNITED KINGDOM), CKJ GRAPHICAL ABSTRACTS EDITOR

One of the top downloaded articles in 2024
The diagnosis of acute interstitial nephritis caused by infection versus antibiotic-induced interstitial nephritis: a narrative review

DISCOVER OUR OCTOBER ISSUE OF CKJ 
Fully open access
We thank Mayleen Laico from The Philippines for providing the cover photo. The title of the painting is “Stained”.  It is inspired by the immunofluorescent staining of glomeruli done in the histopathologic evaluation of glomerular disease.

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Content:
Anemia and iron deficiency in post-kidney transplantation: an unsolved challenge
Hypertension burden in CKD: is nocturnal hypertension the primary culprit?
CRISPR and gene editing for kidney diseases: where are we?
The impact of metabolic dysfunction-associated steatotic liver disease (MASH) on the high risk of cardiovascular disease in CKD: interconnections and management
Bioengineered T-cell therapies for precision immunotherapy in renal transplantation, autoimmune relapse, and sensitization
Citrate and calcium kidney stones
10 tips on how to take a proper family history in CKD patient care
Pathways to translation for nanomedicine in nephrology
General clinical nephrology
Global burden and trends of stroke attributable to kidney dysfunction from 1990 to 2021
Identification of early predictors of clinical remission in primary membranous nephropathy: a post hoc analysis of the STARMEN trial
Telitacicept versus mycophenolate mofetil in IgA nephropathy: a real-world comparative study of efficacy, renal outcomes and safety
Kidney Failure Risk Equation performance according to the etiology of chronic kidney disease in the CKD-CAREMEAU cohort
Classical and mannose-binding lectin complement pathway activation in patients with ANCA-associated vasculitis
Novel therapies improve prognosis of IgAN and limit the applicability of the International IgA Nephropathy Prediction Tool
The Portuguese Albuminuria Study: national insights into prevalence and risk factors
Predicting prognosis in ANCA-associated vasculitis with kidney involvement
A novel CT-based radiomics approach for kidney function evaluation in ADPKD: a pilot study
Clinical applications and limitations of large language models in nephrology: a systematic review
But how green is it actually? Calculating the environmental footprint of kidney care environmental optimizations within haemodialysis
Acute kidney disease
Drivers of hospital costs in ANCA-associated vasculitis patients with long-term follow-up—a real-world cost analysis
Chronic kidney disease and complications
Management and treatment of chronic kidney disease in the Danish Lolland-Falster Health Study: focus on renoprotection and cardiovascular disease prevention
The impact of hemoadsorption in patients with chronic kidney disease undergoing coronary artery bypass grafting
Effect of spironolactone on cardiovascular and renal outcomes in patients with chronic kidney disease
The Swedish Renal Registry: a nationwide registry for chronic kidney disease of all stages
Exploring the relationship between serum magnesium levels, genetic variants and chronic kidney disease: a prospective study
Social deprivation as a key driver of spatial disparities in end-stage kidney disease incidence
Empagliflozin and fluid balance: results from the SiRENA project
Dapagliflozin use in tolvaptan-treated patients with ADPKD: exploring renal outcomes in a retrospective study
Ryunosuke Nakajima and others
Dialysis
Concordance of symptoms perceived by patients receiving haemodialysis and those reported by nurses and nephrologists: a cross-sectional, multicentre, observational study using the REIN registry
Effect of dialysate bicarbonate on calciprotein particle crystallization time (T50) in hemodialysis patients—the D-Bic study
Jennifer Machacek and others
Difelikefalin for CKD-aP: real world evidence of efficacy and safety in Italian patients
Pediatric nephrology
Growth hormone treatment associates with improved circulating anti-aging protein Klotho and reduced arterial stiffness in children with CKD
Letter to the Editor
Kidney interstitial edema as the central pathophysiological mechanism of NSAKI: a call for reappraisal
Corrections
Correction to: Decongestion in patients with advanced chronic kidney disease coexisting with heart failure
Correction to: Spatially resolved transcriptomic profiling for glomerular and tubulointerstitial gene expression in C3 glomerulopathy
Correction to: The burden of acute kidney disease: an epidemiological review and importance of follow-up care
Correction to: A clinical score to predict recovery in end-stage kidney disease due to acute kidney injury

Content:

Editorial Comment
Special Feature
In Context
CKJ Reviews
ExpandOriginal Articles
Exceptional Case
Letter to the Editor

RECOMMENDED REVIEWS

Elevated exposure to air pollutants accelerates primary glomerular disease progression 
This work is important because air pollution exposure represents a potentially modifiable risk factor for chronic kidney disease progression that can be addressed by regulatory action, personal behaviors and implementation of interventions to prevent or limit exposure.

Renal denervation is effective in reducing blood pressure in patients with CKD 
This article reviews the current evidence on renal denervation in hypertensive patients with CKD. 

The burden of acute kidney disease: an epidemiological review and importance of follow-up care 
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